Culprit or Bystander? The Role of the Fallopian Tube in "Ovarian" High-Grade Serous Carcinoma.

نویسندگان

  • Elizabeth M Swisher
  • Rochelle L Garcia
  • Mark R Kilgore
  • Barbara M Norquist
چکیده

The concurrence of intraepithelial high-grade neoplasia in the fallopian tube with metastatic implants has been taken as evidence of a tubal origin for high-grade serous pelvic carcinomas. In the current issue, Eckert and colleagues perform detailed genomic phylogenetic analyses and demonstrate that some cases of high-grade serous intraepithelial tubal neoplasia are metastatic implants and not precursor lesions. Cancer Discov; 6(12); 1309-11. ©2016 AACR.See related article by Eckert and colleagues, p. 1342.

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عنوان ژورنال:
  • Cancer discovery

دوره 6 12  شماره 

صفحات  -

تاریخ انتشار 2016